Frontline Drugstore - Pain Relief

NOW® D-Flame is a synergistic blend of herbs that can reduce the occasional minor pain resulting from over-exertion or stress. In addition, NOW® D-Flame contains a potent combination of antioxidants that contribute to heart health and proper immune system function. This formula can be used daily for the support of vascular and general health or, occasionally, to alleviate the aches and pains associated with daily life.

What do COX-2 and 5-LOX have to do with pain?

Scientific research has defined naturally occurring enzymes known as Cyclooxygenase-2 (COX-2) and 5-Lipoxygenase (5-LOX) which are implicated in a number of inflammatory conditions. Unlike its more benign and protective sister COX-1 the harmful COX- 2 enzyme is present only during periods of inflammation. COX-2 and 5-LOX form the destructive duo responsible for the production of the proinflammatory type of mediators called eicocasonoids; specifically prostaglandins PGE-2 and leukotrienes.

Those suffering with pain have used non-steroidal anti-inflammatory drugs (NSAIDS) that are available over the counter for years. These medications work by inhibiting the formation of the COX enzymes. The problem is that the NSAIDS block both the harmful COX-2 and the helpful COX-1 enzymes. The COX-1 enzyme functions as a protective mechanism for stomach lining. Long term inhibition of this vital COX-1 enzyme by overuse of these drugs has caused many gastric disorders including bleeding ulcers.

Thankfully at the beginning of time our Creator designed plants that naturally help us with the pain caused by inflammation. These plants have been used for generations by the native peoples of various Eastern and Southeastern countries. Over time, researchers have discovered natural compounds in a number of different plant sources that can significantly support the body’s response to inflammatory conditions.

Which plant extracts are in D-Flame and what do they do?

Holy Basil Extract (Ocimum sanctum
Holy Basil is an annual herb native to India. Considered a sacred herb by the Hindus, it’s used in Ayurvedic medicine for a number of different conditions. Holy Basil contains the natural compound ursolic acid, which helps to support immune system function and has proven useful in dealing with COX-2 & 5-LOX.

Turmeric Extract (Curcuma longa)
Turmeric is a perennial plant found primarily in southern and eastern Asia. It’s one of the most popular and widely used herbs in Ayurvedic medicine. The active component in Turmeric is curcumin, which is a potent antioxidant compound that provides outstanding benefits when dealing COX-2 & 5-LOX.

Ginger Extract (Zingiber officinale)
One of the most popular and widely used herbs today, Ginger is an important part of many different Asian medical systems. Primarily used to detoxify the body and calm an upset stomach, Ginger also supports circulation and has a beneficial effect on COX-2 & 5-LOX.

Green Tea (Camellia sinensis)
Widely distributed throughout southern Asia, Green Tea is also found in Africa. It contains a veritable treasure trove of antioxidant compounds, including polyphenols, which support immune system function. Research shows that one particular polyphenol, epigallocatechin gallate (EGCG), is over 200 times more powerful than vitamin E!

Boswellin (Boswellia serrata)
This large tree is native to India and yields a gummy resin with a wide variety of applications. One of the most well-used herbs in Ayurvedic medicine, Boswellin contains boswellic acids, which support healthy circulation and work to deactivate certain chemical triggers often associated with COX-2 & 5-LOX.

Bromelain
Bromelain is a compound extracted from pineapples that research shows has a number of beneficial effects in dealing with COX-2 & 5-LOX. Bromelain works by breaking down and removing proteins in inflamed tissues.

Side Effects: In rare cases, allergic skin reactions may develop.
Active Ingredients: Calendula officinalis 1X, Hamamelis virginiana 1X, Arnica montana, radix 3X 1.50 g each; Aconitum napellus 3X, Belladonna 3X 1.00 g each; Bellis perennis 1X, Chamomilla 1X, Echinacea angustifolia 1X, Echinacea purpurea 1X 0.50 g each; Millefolium 1X 0.30 g; Hepar sulphuris calcareum 8X 0.25 g; Mercurius solubilis 8X 0.12 g; Symphytum officinale 4X 0.10 g; Hypericum perforatum 6X 0.09 g.

• Reduces pain and inflammation with powerful COX-2 inhibitors
• Relaxes muscles, helps improve movement and flexibility
• Restores soft tissue
• Complete Pain Formula • Maximum strength

SUPER FLEX BACK FORMULA offers you a natural way to reduce back pain so you can enjoy life to the fullest with more range of movement and flexibility. This exclusive formula is really THREE formulas in one COMPLETE product, offering you THREE effective ways to reduce inflammation, soreness and stiffness.

Three Formulas in One!

1. Natural pain relief for the aspirin-sensitive!
SUPER FLEX BACK FORMULA offers a natural alternative for those sensitive to aspirin and ibuprofen. This advanced formula includes a special blend of ingredients that actually inhibits the COX-2 enzyme, responsible for painful back inflammation.

2. Complete formula restores connective tissue!
This unique blend of natural ingredients includes the remarkable MSM (methylsulfonylmethane). Studies show that MSM actually binds water in the cartilage matrix, keeping cartilage between vertebra soft and spongy so it absorbs the pounding of movement and activity.

3. Special ingredients help break the cycle of pain!
Sore muscles respond to pain by contracting, causing even more pain. SUPER FLEX BACK FORMULA can actually help break this vicious cycle of pain. This complete formula contains the herb Kava Kava to induce muscle relaxation. When blended with the mineral magnesium, the effect proves even more beneficial because magnesium is required by your body to counteract muscle contraction, so muscles can relax.
60 Tabs
Not for use by persons under the age of 18. Not for use by women who are pregnant or nursing. If you are taking a prescription drug or have a medical condition, consult a health care practitioner prior to use. Do not exceed recommended dosage. Excessive consumption may impair ability to drive or operate heavy equipment. Not recommended for consumption with alcoholic beverages. Keep out of the reach of children. Store at room temperature.
Take two tablets 3 times daily for the first week or for maximum strength. For maintenance use, take one tablet 3 times daily.
Back pain relief for the aspirin sensitive! Natural formula improves mobility and flexibility!

SUPER FLEX BACK FORMULA offers you a potent blend of natural ingredients known to reduce painful inflammation and restore healthy connective tissue. Add to that, a muscle relaxation blend and you have THREE potent pain fighters in one remarkable back pain product! SUPER FLEX BACK FORMULA can help you live pain free while improving mobility and flexibility.

SUPER FLEX BACK FORMULA - Anti Inflammation Ingredients:

• Turmeric And Ginger: Important phytonutrients that inhibit the COX-2 enzyme, responsible for back inflammation.
• Trans-resveratrol: Powerful phytonutrient that helps reverse free radical damage to vertebra tissue and helps inhibit COX-2.
• Boswellin: Proven to reduce inflammation.

SUPER FLEX BACK FORMULA - Connective Tissue Repair Ingredients:

• Glucosamine: Known to restore connective tissue and maintain synovial fluid in vertebra tissue.
• MSM (methylsulfonylmethane): Helps connective tissue absorb fluid to cushion the shock of movement and activity.

SUPER FLEX BACK FORMULA - Muscle Relaxation Ingredients:

Considering that most health issues from a skinned knee, twisted ankle or even normal wear and tear involve some level of pain, it only makes sense to decipher the mechanism behind this feeling and find a means to manage it. For centuries, various remedies provided some pain relief until a breakthrough occurred in the discovery that the hormone-like compounds called prostaglandins, which are the cause of inflammation and thus the producers of pain, could be blocked. By inhibiting an enzyme known as Cyclooxygenase-2 (COX-2), which triggers the release of prostaglandins, there exists a solution to pain management.
60 Caps

See bottle for specific useage.
What’s in C-2 Relief™
While COX-2 inhibition may seem to clearly describe one pharmacological effect of several common and widely recognized natural products, such a benefit seems in favor of the following compounds serving as natural modulators of pain:

Syzygium Aromaticum, more commonly known as Cloves, have natural anesthetic properties.

White Willow Bark contains salicylic acid, which is the active ingredient in aspirin. Aspirin was originally derived from white willow bark but is now made synthetically.

Curcuminoids are powerful anti-inflammatory agents.

Morinda Officinalis contains a wide variety of beneficial phytochemicals, some of which are not found in any other known plant. Phytochemicals are natural chemicals found in plants that work synergistically to enhance biologically the expression of each individual component found in Noni including its uses for pain and inflammation.

Planetary Herbals powerful Minor Pain Relief™ unites age-old tradition with modern science. This comprehensive formula combines corydalis, a primary minor pain relieving herb extensively used in China, with willow bark, traditionally used in the West. Also included are powerful COX-II inhibitors from ginger root and Humulex™, a hops extract for relief of minor pain from daily activities or overexertion.
60 Tabs
Do not use this product if you are pregnant, breastfeeding or may become pregnant.

Chronic use of COX-II inhibitors may temporarily impair female fertility.

Continuous use of this product with non-steroidal anti-inflammatory drugs such as aspirin, acetaminophen, or ibuprofen may increase the risk of gastric erosion caused by these compounds.

The exclusive, patented processing (U.S. Patent #6,551,626) used to create Petadolex Pro-Active removes toxins naturally present in butterbur, making it the ONLY safe form available.

Children 2 years or older: Dissolve 1-2 tablets in mouth every 2 hours until relieved.
100% natural, Aspirin free, Sugar free